Skip to main content

ETİK

Bioetik; biyotıp ve biyomedikal araştırmalarda ortaya çıkan sosyal ve yasal sorunların incelenmesidir.

Biyoetik Temeller

Sağlık hizmetlerinde biyoetik karar vermenin dört ayağı vardır. Bunlar:

1. Özerklik – kendi kararlarınızı verme yeteneği. Hastanın hakkı var yaparak tedavi sırasında nelerin olup olmayacağını belirlemektir. bilgilendirilmiş, zorlamasız karar (rıza).

2. Hayırseverlik - bir hayırseverlik veya nezaket eylemi. Bir sağlık profesyoneli şart başka hiçbir amacı olmadan hastanın yararına hareket etmek.

3. Zarar vermeme – “zarar verme”. Sağlık çalışanı zarar vermemeli hasta.

4. Adalet - sağlık kararlarında adalet sağlamak. Bir sağlık uzmanı kaynakların eşit dağılımı ile tüm bireylere eşit davranmalıdır.

Bilimsel araştırmaların uluslararası kabul görmesi için metodolojik ve anlamsal uyumun yanı sıra etik ilkelerin standardizasyonundan da bahsedilmektedir.

Bu bağlamda sunumun sonunda kısaca hatırlatacağımız ana ilkeler “zarar verme”, “saygı”, “gizlilik”, “bilgilendirilmiş onay” ve “dürüstlük” dür.

• YÖK,Bilimsel Araştırma Ve Yayın Etiği Yönergesi

https://www.yok.gov.tr/Sayfalar/Kurumsal/mevzuat/bilimsel-arastirma-ve-etikyonetmeligi.aspx

• Dünya Tıp Birliği (WMA) Helsinki Bildirgesi

https://jag.journalagent.com/aot/Helsinki_Decleration_tur.pdf

• HELSİNKİ'NİN DTB DEKLARASYONU

https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for medical-research-involving-human-subjects/

• Hayvan Deneyleri Etik Kurullarının Çalışma Usul Ve Esaslarına Dair Yönetmelik

https://www.resmigazete.gov.tr/eskiler/2014/02/20140215-6.ht

Popular posts from this blog

MUTATIONS AND DNA REPAIR MECHANISIMS

Types Of Mutations • Spontaneous mutations: occur because of natural processes in cells, for example DNA replication errors. • Induced mutations: occur because of interaction of DNA with an outside agent or mutagen that causes DNA damage. the importance of mutations  genetic variation  deleterious or advantageous  mutations in germ cells can lead to heritable genetic disorders. mutations in somatic cells may lead to acquired diseases such as cancer or neurodegenerative disorders.  tools for molecular biologists in characterizing the genes.  • Mutations that alter a single nucleotide pair are called point mutations.  Other Kinds of Mutations  expansions of trinucleotide repeats,  extensive insertions and deletions major chromosomal rearrangements • Transition mutations replace one pyrimidine base with another, or one purine base with another.  • Transversion mutations replace a pyrimidine with a purine or vice versa. Sickle cell anemia mutatio...

CONVENTIONAL METHODS IN MOLECULAR BIOLOGY

  Comparison of conventional and modern techniques  • In conventional techniques, isolation and manipulation of DNA or RNA is not applied.  • Experiments are set based on phenotypic characters and the results are expressed based on observations or quantitative measurements.  • The basic materials of modern biotechnology are nucleic acids (NA) and proteins (P).  • NA and P are isolated from tissue, purified and subjected to certain processes.  • NAs are amplified in bacteria or by polymerase chain reaction (PCR), cut with restriction enzymes and hybridized with a different NA, If necessary, or run on an Agarose Gel Electrophoresis, stained and visualized.  • Likewise, proteins are purified, run on an SDS-PAGE gel, stained/immunoblotted and visualized.  Proof of transforming factor   In vivo Experiment  • In 1928, Frederick Griffith described a transforming principle that transmitted the ability of bacteria to cause pneumonia in mice. “tra...

THE STRUCTURE OF PROTEIN

•In proteins, the links of the chain are the amino acids specified by the genetic code.  • Whereas DNA is composed of only four different nucleotides, proteins have a repertoire of 20 common amino acids and, in some special cases, two additional amino acids. • The only difference between any two amino acids is in their different SIDE CHAINS.  • Each side chain has distinct properties, including  • charge, hydrophobicity, and polarity.  • SIDE CHAINS GIVES EACH PROTEIN ITS CHARACTERISTIC STRUCTURE AND FUNCTION. • Amino acids, joined together by peptide bonds, form the primary structure of a protein.  • THE AMINO GROUP OF ONE MOLECULE REACTS WITH THE CARBOXYL GROUP OF THE OTHER IN A CONDENSATION REACTION RESULTING IN THE ELIMINATION OF WATER AND THE FORMATION OF A DIPEPTIDE. • Protein primary structure is divided into two main components,  • the polypeptide backbone that has the same composition in all proteins, and  • THE VARIABLE SIDE CHAIN GROUPS. Tra...